Bis(pinacolato)diboron

Bis(pinacolato)diboron (B2pin2)

CAS No. 73183-34-3

Molecular weight: 253.94

Purity: 99%

Appearance: White crystalline powder

Packaging: 20 kg paper bag / 20 kg craft paper bag

Applications: Due to its high stability in air and humid environments, bis(pinacolato)diboron (B2pin2) is one of the most commonly used diborane reagents in organic synthesis. It is employed in the construction of tetramethylpyrrolidino nitrooxy scaffolds for the synthesis of paramagnetic heterocyclic compounds via Suzuki coupling reactions. It also serves as a reagent for platinum-catalyzed cis-diborylation of alkynes and alkenes; additionally, it can be utilized in palladium-catalyzed boronation reactions of aromatic hydrocarbons. Furthermore, it acts as a substrate in a novel reaction catalyzed by palladium that converts 1,6-alkynediynes into highly allylic alkylboronates.

Application: Due to its high stability in air and humid environments, bis(pinacolato)diboron (B2pin2) is the most commonly used diborane reagent in organic synthesis. It is employed to construct a tetramethylpyrrolidine nitrooxide scaffold for synthesizing paramagnetic heterocyclic compounds via the Suzuki coupling reaction. This reagent is also used in platinum-catalyzed cis orthoboration of acetylene and olefins; additionally, it can be utilized in palladium-catalyzed boronization reactions of aromatic hydrocarbons. Furthermore, it serves as a novel substrate for palladium-catalyzed cyclization of 1,6-alkynes, enabling the efficient synthesis of high allyl alkyl borate esters.